Follow all the action from the big Guinness Premiership top-of-the-table clash as it happens.

Can Toby Booth's men end Saracens' unbeaten record in the league this season?

In the only change to the Exiles' team that beat Brive in the Heineken Cup last weekend, Delon Armitage comes in at  full-back with Peter Hewat switching to left wing and John Rudd dropping to the replacements' bench.

London Irish:  15 Delon Armitage; 14 Tom Homer; 13 Elvis Seveali’i; 12 Seilala Mapusua; 11 Peter Hewat; 10 Chris Malone; 9 Alfredo Lalanne; 1 Clarke Dermody; 2. David Paice, 3. Paulica Ion; 4. Nick Kennedy; 5 Bob Casey (capt); 6 Richard Thorpe; 7 Steffon Armitage; 8 Chris Hala’Ufia.

Replacements: 16 Danie Coetzee; 17 Dan Murphy; 18 Faan Rautenbach; 19 Kieran Roche; 20 George Stowers; 21 John Rudd; 22 Peter Richards; 23 Ryan Lamb.

Saracens: 15 Alex Goode, 14 Rodd Penney, 13 Kameli Ratuvou, 12 Brad Barritt, 11 Chris Wyles, 10 Glen Jackson, 9 Justin Marshall, 1 Matias Aguero, 2 Fabio Ongaro, 3 Richard Skuse, 4 Steve Borthwick (c), 5 Hugh Vyvyan, 6 Wikus van Heerden, 7 Justin Melck, 8 Ernst Joubert.

Replacements: 16 Schalk Brits, 17 Rhys Gill, 18 Carlos Nieto, 19 Mouritz Botha, 20 Andy Saull, 21 Moses Rauluni, 22 Derick Hougaard, 23 Richard Haughton.